Man-yeon Choi
Courtesy Faculty, Research Entomologist

My research focus is on insect proteomics, molecular physiology, and chemical ecology to develop novel pest managements and to understand biological questions.

USDA-ARS
Department of Crop and Soil Science
Department of Horticulture
Graduate School
Entomology
USDA-ARS
3420 NW Orchard Ave.
Corvallis, OR 97330
United States
541-738-4026

Research

  1. Development of RNA inference (RNAi)-based insecticide to protect small fruits and nursery crops.
  2. Insect neuropeptides and G-protein coupled receptors (GPCRs), and discovery of bioactive proteins/compounds using GPCR-based screening and structural modeling.
  3. Identification of semiochemicals including insect pheromones and biosynthetic pathway, and application to pest management.
  4. Functional diversity and evolution of neurohormones and their receptors (i.e., GPCRs) from insects to mammals.

Biography

 

Education:

Ph.D. The University of Tokyo (Insect Molecular Biology & Physiology)

M.S. Seoul National University (Insect Physiology)

B.S. Seoul National University (Entomology)

 

 
I accept graduate students for Horticulture

Publications

Peer-Reviewed (selected)

Seung-Joon Ahn, Ruth Martin, Sujaya Rao, Man-Yeon Choi. 2017. Neuropeptides predicted from the transcriptome analysis of the gray garden slug, Deroceras reticulatum. Peptides (under review).

Man-Yeon Choi, Siew Bee Tang, Seung-Joon Ahn, Kaushalya G. Amarasekare, Peter Shearer, Jana C. Lee. 2017. Effect of non-nutritive sugars to decrease the survivorship of spotted wing drosophila, Drosophila suzukii. J. Insect Physiol. 99:86-94.

Seung-Joon Ahn, Ruth Martin, Sujaya Rao, Man-Yeon Choi. 2017. The complete mitochondrial genome of the gray garden slug Deroceras reticulatum (Gastropoda: Pulmonata: Stylommatophora). Mitochondrial DNA Part B (in press).

Man-Yeon Choi, Seung-Joon Ahn, A. Young Kim, Youngho Koh. 2017. Identification and characterization of pyrokinin and CAPA peptides, and corresponding GPCRs from spotted wing drosophila, Drosophila suzukii. General and Comparative Endocrinology (in press).

Young Ha Kima, Joon Haeng Hur, Gwan Seok Lee, Man-Yeon Choi, Young Ho Koh. 2016. Rapid and highly accurate detection of Drosophila suzukii, spotted wing Drosophila (Diptera: Drosophilidae) by loop-mediated isothermal amplification assays. J. Asia-Pacific Entomology 19:1211-1216.

Man-Yeon Choi, Seung-Joon Ahn, Kye-Chung Park, Robert Vander Meer, Ring Carde, Russell Jurenka. 2016. Trasi of Heliothine moths contain adldehydes and butyrate esters as potential pheromones. J. Chemical Ecology 42(5):425-432.

Phuong Nguyen, A Young Kim, Jin Kyo Jung, Kelly M. Donahue, Chuleui Jung, Man-Yeon Choi*, Young Ho Koh*. 2016. The biochemical adaptations of Spotted wing Drosophila, Drosophila suzukii, to fresh fruits; reduced fructose concentrations and glutathione-S transferase activities. J. Economic Entomology 109:973-981.

Man-Yeon Choi, Neil Sanscrainte, Alden Estep, Robert Vander Meer and James Becnel. 2015. Identification and expression of the pyrokinin/PBAN gene family in the sand fly, Phlebotomus papatasi. J. Insect Physiology 79, 55-62.

Man-Yeon Choi and Vander Meer, Robert. 2015 Alarm pheromone biosynthesis and functional parsimony in the fire ant Solenopsis invicta. Physiological Entomology 40(3), 196-204. 

Man-Yeon Choi, Renè Köhler, Robert K. Vander Meer, Susanne Neupert, and Reinhard Predel. 2014. Identification and Expression of Capa Gene in the Fire Ant, Solenopsis invicta. PLoS ONE 9(4) e94274.

Man-Yeon Choi, Alden Estep, Neil Sanscrainte, James Becnel and Robert Vander Meer. 2013. Identification and expression of PBAN/diapause hormone and GPCRs from Aedes aegypti. Molecular and Cellular Endocrinology 375: 113-120.

Steven M. Valles, Sanford D. Porter, Man-Yeon Choi, David H. Oi. 2013. Successful transmission of Solenopsis invicta virus 3 to Solenopsis invicta fire ant colonies in oil, sugar, and cricket bait formulations. Journal of Invertebrate Pathology 113:198-204.

Tyas Nusawardani, J.A. Kroemer, Man-Yeon Choi, and R.A. Jurenka. 2013. Identification and characterization of the pyrokinin/pheromone biosynthesis activating neuropeptide family of G protein-coupled receptors from Ostrinia nubilalis. Insect Molecular Biology 22: 331-340.

Man-Yeon Choi and Vander Meer, Robert K. 2012. Ant trail pheromone biosynthesis is triggered by a neurohormone. PLoS One, 7 (11) e50400.

Man-Yeon Choi, Robert K. Vander Meer, Monique Coy, and Michael E. Scharf, 2012. Phenotypic impacts of PBAN RNA interference in an ant, Solenopsis invicta, and a moth, Helicoverpa zea. Journal of Insect Physiology 58:1159-1165.

Man-Yeon Choi and Robert K. Vander Meer. 2012. Molecular structure and diversity of PBAN/Pyrokinin family peptides in ants. Frontiers in Endocrinology 3 (32): 1-8.

Robert K. Vander Meer and Man-Yeon Choi. 2011. Pheromone Biosynthesis Activating Neuropeptide (PBAN)/Pyrokinin Family of Peptides and Fire Ants, Solenopsis spp. Formosan Entomologist 31: 1-15.

Man-Yeon Choi Vander Meer, K. Robert, DeWayne Shoemaker, and Steven M. Valles, 2011. PBAN gene architecture and expression in the fire ant, Solenopsis invicta. Journal of Insect physiology 57:161-165.

Man-Yeon Choi, Robert K. Vander Meer and Steven M. Valles. 2010. Molecular diversity of PBAN family peptides from fire ants. Archives of Insect Biochemistry and Physiology 74: 67-80.

Man-Yeon Choi and Russell A. Jurenka. 2010. Site-directed mutagenesis and PBAN activation of the Helicoverpa zea PBAN-receptor. FEBS letter 584:1212-1216.

Robert K. Vander Meer, C.A. Preston, and Man-Yeon Choi. 2010. Isolation of a Pyrazine Alarm Pheromone Component from the Fire Ant, Solenopsis invicta. Journal of Chemical Ecology 36:163-170.

Man-Yeon Choi and Robert K. Vander Meer. 2009. Identification of a new member of PBAN/pyrokinin family from fire ant, Solenopsis invicta. Insect Molecular Biology 18:161-169.

Man-Yeon Choi, Ashok Raina and Robert K. Vander Meer. 2009. PBAN/Pyrokinin peptides in the central nervous system of the fire ant, Solenopsis invicta. Cell and Tissue Research 335:431-439.

Man-Yeon Choi, Hangkyo Lim, Kye Chung Park, Richard Adlof, Shifa Wang Aijun Zhang and Russell Jurenka. 2007a. Identification and biosynthesis of hydrocarbon sex pheromone in Utetheisa ornatrix (Lepidoptera: Arctiidae). Journal of Chemical Ecology, 33: 1336-1345.

Peter S. Stern, Lian Yu, Man-Yeon Choi, Russell A. Jurenka, Ada Rafaeli, 2007. Molecular modeling of the biding of Pheromone Biosynthesis Activating Neuropeptide (PBAN) to its receptor. Journal of Insect Physiology, 53:803-818.

Rafaeli, A., Bober, R., Becker, L., Choi, Man-Yeon, Feurst, E.-J., Jurenka, R. 2007. Spatial Distribution and Differential Expression of the PBAN receptor in Tissues of Adult Helicoverpa spp. (Lepidoptera: Noctuidae). Insect Molecular Biology, 16(3): 287-293.

Man-Yeon Choi, Emily Feurst, Ada Rafaeli and Russell Jurenka. 2007. Role of extracellular domains in PBAN/Pyrokinin GPCRs from insects using chimera receptors. Insect Biochemistry and Molecular Biology 37: 296-306.

Man-Yeon Choi and Russell A. Jurenka. 2006. Role of extracellular Ca2+ and Calcium Channel activated by a GPCR regulating pheromone production in Helicoverpa zea. Annals of Entomological Society of America 99(5): 905-909.

Man-Yeon Choi and Russell A. Jurenka. 2006. C75, a fatty acid synthase inhibitor, decreases feeding activity and pheromone production in a moth, Helicoverpa zea. Journal of Asia-Pacific Entomology 9: 43-48.

Man-Yeon Choi, Astrid Groot and Russell A. Jurenka. 2005. Pheromone Biosynthetic pathways in the moths Heliothis virescens and Heliothis subflexa. Archives Insect Biochemistry and Physiology, 59, 53-58.

Man-Yeon Choi, Jae Min Lee, Kyeung Sik Han and Kyung Saeng Boo. 2004. Identification of a new member of PBAN family and immunoreativity of central nervous system in Adoxophyes sp. (Lepidoptera: Tortricidae). Insect Biochemistry and Molecular Biology 34(9), 927-935.

Man-Yeon Choi and Russell A. Jurenka. 2004. PBAN stimulation of Pheromone biosynthesis by inducing Calcium influx in pheromone glands of Helicoverpa zea. Journal of Insect Physiology 50, 555-560.

Man-Yeon Choi, Emily-Jean Fuerst, Ada Rafaeli, Russell Jurenka. 2003. Identification of a pheromone biosynthesis activating neuropeptide G protein –coupled receptor in pheromone gland of the moth, Helicoverpa zea. PNAS 100 (17): 9721-9726.

Russell A. Jurenka, Mitko Subchev, José-Luis Abad, Man-Yeon Choi and Gemma Fabriás. 2003. Sex pheromone biosynthetic pathway disparlure in the gypsy moth, Lymantria dispar. PNAS100 (3): 809-814.

Man-Yeon Choi, Kyeung-Sik Han, Kyung Saeng Boo and Russell A. Jurenka. 2002. Pheromone Biosynthetic pathways in the moths Helicoverpa zea and Helicoverpa assulta. Insect Biochemistry & Molecular Biology 32: 1353-1359.

Seung Joon Ahn, Man-Yeon Choi and Kyung Saeng Boo. 2002. Mating effect on sex pheromone production of the Oriental tobacco budworm, Helicoverpa assulta. Journal of Asia-Pacific Entomology 5: 43-48.

Man-Yeon Choi, Ada Rafaeli and Russell A. Jurenka. 2001. Pyrokinin/PBAN-like peptides in the central nervous system of Drosophila melanogaster. Cell and Tissue Research 306:459-465.

Boo, Kyung Saeng, Man Yeon Choi, In Bum Chung, V. F. Eastop, J. A. Pickett, L. J. Wadhams and C. M. Woodcock. 2000. Sex Pheromone of the Peach Aphid, Tuberocephalus momonis, and Optimal Blends for Trapping Males and Females in the Field. Journal of Chemical Ecology 26: 601-609.

Man-Yeon Choi. 1999. Identification and determination of the partial cDNA encoding the pheromone biosynthesis activating neuropeptide in Helicoverpa armigera. Journal of Asia-Pacific Entomology 2: 175-180.

Man-Yeon Choi, M. Tanaka, H. Kataoka, K. S. Boo and S. Tatsuki. 1998. Isolation and identification of the cDNA encoding the pheromone biosynthesis activating neuropeptide (PBAN) of oriental tobacco budworm, Helicoverpa assulta (Lepidoptera: Noctuidae). Insect Biochemistry and Molecular Biology 28, 759-766.

Man-Yeon Choi, S. Tatsuki and K. S. Boo. 1998. Regulation of sex pheromone biosynthesis in the Oriental Tobacco Budworm, Helicoverpa assulta (Lepidoptera: Noctuidae). Journal of Insect Physiology 44, 653-658.

Book
Boo, Kyung Saeng, Park, Kye Chung, Kim, Yonggyun, Choi, Man-Yeon. 2005. “Insect Hormones and Physiology”, 896 pp. Seoul National University Press, Seoul.

Patents

Man-Yeon Choi and Robert Vander Meer, 2016. Bioactive peptides having insecticide activity, application #: 62131342-pending

Robert Vander Meer, Man-Yeon Choi. 2017. Lepidopteran Moth Control Using Double-Stranded RNA Constructs, US Patent No US9617542.

Robert Vander Meer, Man-Yeon Choi. 2015. Control of insect pests through RNAi of Pheromone Biosynthesis Activating Neuropeptide Receptor, Patent No US9000145.

Robert Vander Meer and Man-Yeon Choi, 2013. Formicidae (Ant) control using double-stranded RNA constructs, 2013, Patent No US8575328.

Public releases
Pheromone Research May Lead to New Insect Control Methods” Entomology Today in Entomology Society of America. April, 2014

Targeting Pheromones in Fire Ants” In News and Events of Agricultural Research Service of USDA, April 2014.