College of Agricultural Sciences

T. - G. Lim, Lee, B. Kyung, Kwon, J. Yeon, Jung, S. Keun, and Lee, K. Won, “Acrylamide up-regulates cyclooxygenase-2 expression through the MEK/ERK signaling pathway in mouse epidermal cells.”, Food Chem Toxicol, vol. 49, no. 6, pp. 1249-54, 2011.

A. K. Ehrlich, Pennington, J. M., Wang, X., Rohlman, D., Punj, S., Löhr, C. V., Newman, M. T., Kolluri, S., and Kerkvliet, N. I., “Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice.”, J Immunol, vol. 196, no. 1, pp. 264-73, 2016.

A. K. Ehrlich, Pennington, J. M., Tilton, S., Wang, X., Marshall, N. B., Rohlman, D., Funatake, C., Punj, S., O'Donnell, E. F., Yu, Z., Kolluri, S., and Kerkvliet, N. I., “AhR activation increases IL-2 production by alloreactive CD4 T cells initiating the differentiation of mucosal-homing Tim3 Lag3 Tr1 cells.”, Eur J Immunol, vol. 47, no. 11, pp. 1989-2001, 2017.

S. Dagdeviren, Jung, D. Young, Lee, E., Friedline, R. H., Noh, H. Lim, Kim, J. Hun, Patel, P. R., Tsitsilianos, N., Tsitsilianos, A. V., Tran, D. A., Tsougranis, G. H., Kearns, C. C., Uong, C. P., Kwon, J. Yeon, Muller, W., Lee, K. Won, and Kim, J. K., “Altered Interleukin-10 Signaling in Skeletal Muscle Regulates Obesity-Mediated Inflammation and Insulin Resistance.”, Mol Cell Biol, vol. 36, no. 23, pp. 2956-2966, 2016.

E. F. O'Donnell, Saili, K. S., Koch, D. C., Kopparapu, P. R., Farrer, D., Bisson, W. H., Mathew, L. K., Sengupta, S., Kerkvliet, N. I., Tanguay, R. L., and Kolluri, S. Kumar, “The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor.”, PLoS One, vol. 5, no. 10, 2010.

S. Punj, Kopparapu, P., Jang, H. Sang, Phillips, J. Lynne, Pennington, J. M., Rohlman, D., O'Donnell, E. F., Iversen, P. L., Kolluri, S., and Kerkvliet, N. I., “Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease.”, PLoS One, vol. 9, no. 2, p. e88726, 2014.

S. Ho Shin, Seo, S. Gwon, Min, S., Yang, H., Lee, E., Son, J. Eun, Kwon, J. Yeon, Yue, S., Chung, M. - Y., Kim, K. - H., Cheng, J. - X., Lee, H. Joo, and Lee, K. Won, “Caffeic acid phenethyl ester, a major component of propolis, suppresses high fat diet-induced obesity through inhibiting adipogenesis at the mitotic clonal expansion stage.”, J Agric Food Chem, vol. 62, no. 19, pp. 4306-12, 2014.

H. Kang, Lee, C. Hyung, Kim, J. Rhan, Kwon, J. Yeon, Seo, S. Gwon, Han, J. Gab, Kim, B. Gon, Kim, J. - E., and Lee, K. Won, “Chlorella vulgaris Attenuates Dermatophagoides Farinae-Induced Atopic Dermatitis-Like Symptoms in NC/Nga Mice.”, Int J Mol Sci, vol. 16, no. 9, pp. 21021-34, 2015.

C. J. Funatake, Marshall, N. B., Steppan, L. B., Mourich, D. V., and Kerkvliet, N. I., “Cutting edge: activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of regulatory T cells.”, J Immunol, vol. 175, no. 7, pp. 4184-8, 2005.

J. - E. Kim, Kwon, J. Yeon, Seo, S. Kwon, Son, J. Eun, Jung, S. Keun, Min, S. Yun, Hwang, M. Kyung, Heo, Y. - S., Lee, K. Won, and Lee, H. Joo, “Cyanidin suppresses ultraviolet B-induced COX-2 expression in epidermal cells by targeting MKK4, MEK1, and Raf-1.”, Biochem Pharmacol, vol. 79, no. 10, pp. 1473-82, 2010.

T. - G. Lim, Kwon, J. Yeon, Kim, J., Song, N. Ry, Lee, K. Mi, Heo, Y. - S., Lee, H. Joo, and Lee, K. Won, “Cyanidin-3-glucoside suppresses B[a]PDE-induced cyclooxygenase-2 expression by directly inhibiting Fyn kinase activity.”, Biochem Pharmacol, vol. 82, no. 2, pp. 167-74, 2011.

K. Won Cho, Lee, O. - H., Banz, W. J., Moustaid-Moussa, N., Shay, N. F., and Kim, Y. - C., “Daidzein and the daidzein metabolite, equol, enhance adipocyte differentiation and PPARgamma transcriptional activity.”, J Nutr Biochem, vol. 21, no. 9, pp. 841-7, 2010.

N. Joo Kang, Lee, K. Won, Kwon, J. Yeon, Hwang, M. Kyung, Rogozin, E. A., Heo, Y. - S., Bode, A. M., Lee, H. Joo, and Dong, Z., “Delphinidin attenuates neoplastic transformation in JB6 Cl41 mouse epidermal cells by blocking Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling.”, Cancer Prev Res (Phila), vol. 1, no. 7, pp. 522-31, 2008.

J. Yeon Kwon, Lee, K. Won, Kim, J. - E., Jung, S. Keun, Kang, N. Joo, Hwang, M. Kyung, Heo, Y. - S., Bode, A. M., Dong, Z., and Lee, H. Joo, “Delphinidin suppresses ultraviolet B-induced cyclooxygenases-2 expression through inhibition of MAPKK4 and PI-3 kinase.”, Carcinogenesis, vol. 30, no. 11, pp. 1932-40, 2009.

B. Mahadevan, Luch, A., Bravo, C. F., Atkin, J., Steppan, L. B., Pereira, C. B., Kerkvliet, N. I., and Baird, W. M., “Dibenzo[a,l]pyrene induced DNA adduct formation in lung tissue in vivo.”, Cancer Lett, vol. 227, no. 1, pp. 25-32, 2005.

J. - Y. Choi, Oughton, J. A., and Kerkvliet, N. I., “Functional alterations in CD11b(+)Gr-1(+) cells in mice injected with allogeneic tumor cells and treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.”, Int Immunopharmacol, vol. 3, no. 4, pp. 553-70, 2003.

K. M. Moyes, Drackley, J. K., Morin, D. E., Bionaz, M., Rodriguez-Zas, S. L., Everts, R. E., Lewin, H. A., and Loor, J. J., “Gene network and pathway analysis of bovine mammary tissue challenged with Streptococcus uberis reveals induction of cell proliferation and inhibition of PPARgamma signaling..”, BMC Genomics, vol. 10, p. 542, 2009.

L. Yee Cheong, Suk, S., Thimmegowda, N. R., Chung, M. - Y., Yang, H., Seo, S. Gwon, Shwetha, B., Kim, J. - E., Kwon, J. Yeon, Kim, B. Yeon, and Lee, K. Won, “Hirsutenone Directly Targets PI3K and ERK to Inhibit Adipogenesis in 3T3-L1 Preadipocytes.”, J Cell Biochem, vol. 116, no. 7, pp. 1361-70, 2015.

Y. Li, Mezei, O., and Shay, N. F., “Human and murine hepatic sterol-12-alpha-hydroxylase and other xenobiotic metabolism mRNA are upregulated by soy isoflavones.”, J Nutr, vol. 137, no. 7, pp. 1705-12, 2007.

Y. Li, Ross-Viola, J. S., Shay, N. F., Moore, D. D., and Ricketts, M. - L., “Human CYP3A4 and murine Cyp3A11 are regulated by equol and genistein via the pregnane X receptor in a species-specific manner.”, J Nutr, vol. 139, no. 5, pp. 898-904, 2009.

S. Dagdeviren, Jung, D. Young, Friedline, R. H., Noh, H. Lim, Kim, J. Hun, Patel, P. R., Tsitsilianos, N., Inashima, K., Tran, D. A., Hu, X., Loubato, M. M., Craige, S. M., Kwon, J. Yeon, Lee, K. Won, and Kim, J. K., “IL-10 prevents aging-associated inflammation and insulin resistance in skeletal muscle.”, FASEB J, vol. 31, no. 2, pp. 701-710, 2017.

J. Yeon Kwon, Seo, S. Gwon, Yue, S., Cheng, J. - X., Lee, K. Won, and Kim, K. - H., “An inhibitory effect of resveratrol in the mitotic clonal expansion and insulin signaling pathway in the early phase of adipogenesis.”, Nutr Res, vol. 32, no. 8, pp. 607-16, 2012.

S. Gwon Seo, Yang, H., Shin, S. Ho, Min, S., Kim, Y. A., Yu, J. Gak, Lee, D. Eun, Chung, M. - Y., Heo, Y. - S., Kwon, J. Yeon, Yue, S., Kim, K. Hong, Cheng, J. - X., Lee, K. Won, and Lee, H. Joo, “A metabolite of daidzein, 6,7,4'-trihydroxyisoflavone, suppresses adipogenesis in 3T3-L1 preadipocytes via ATP-competitive inhibition of PI3K.”, Mol Nutr Food Res, vol. 57, no. 8, pp. 1446-55, 2013.

J. - E. Kim, Kwon, J. Yeon, Lee, D. Eun, Kang, N. Joo, Heo, Y. - S., Lee, K. Won, and Lee, H. Joo, “MKK4 is a novel target for the inhibition of tumor necrosis factor-alpha-induced vascular endothelial growth factor expression by myricetin.”, Biochem Pharmacol, vol. 77, no. 3, pp. 412-21, 2009.

W. H. Bisson, Koch, D. C., O'Donnell, E. F., Khalil, S. M., Kerkvliet, N. I., Tanguay, R. L., Abagyan, R., and Kolluri, S. Kumar, “Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands.”, J Med Chem, vol. 52, no. 18, pp. 5635-41, 2009.