Found 23 results
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Journal Article
A. Larkin, Siddens, L. K., Krueger, S. K., Tilton, S. C., Waters, K. M., Williams, D. E., and Baird, W. M., Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin, Toxicology and Applied Pharmacology, vol. 267, no. 2, pp. 192 - 199, 2013.
S. C. Tilton, Tal, T. L., Scroggins, S. M., Franzosa, J. A., Peterson, E. S., Tanguay, R. L., and Waters, K. M., Bioinformatics resource manager v2.3: an integrated software environment for systems biology with microRNA and cross-species analysis tools, BMC Bioinformatics, vol. 13, no. 1, p. 311, 2012.
C. von Neubeck, Shankaran, H., Karin, N. J., Kauer, P. M., Chrisler, W. B., Wang, X., R. Robinson, J., Waters, K. M., Tilton, S. C., and Sowa, M. B., Cell type-dependent gene transcription profile in a three-dimensional human skin tissue model exposed to low doses of ionizing radiation: Implications for medical exposures, Environmental and Molecular Mutagenesis, vol. 53, no. 4, pp. 247 - 259, 2012.
J. G. Teeguarden, Mikheev, V. B., Minard, K. R., Forsythe, W. C., Wang, W., Sharma, G., Karin, N., Tilton, S. C., Waters, K. M., Asgharian, B., Price, O. R., Pounds, J. G., and Thrall, B. D., Comparative iron oxide nanoparticle cellular dosimetry and response in mice by the inhalation and liquid cell culture exposure routes, Particle and Fibre Toxicology, vol. 1129871397757364843141613724956113181942141321356461541073447, no. 1Suppl 1, 2014.
B. D. Aevermann, Pickett, B. E., Kumar, S., Klem, E. B., Agnihothram, S., Askovich, P. S., Bankhead, A., Bolles, M., Carter, V., Chang, J., Clauss, T. R. W., Dash, P., Diercks, A. H., Eisfeld, A. J., Ellis, A., Fan, S., Ferris, M. T., Gralinski, L. E., Green, R. R., Gritsenko, M. A., Hatta, M., Heegel, R. A., Jacobs, J. M., Jeng, S., Josset, L., Kaiser, S. M., Kelly, S., G. Law, L., Li, C., Li, J., Long, C., Luna, M. L., Matzke, M., McDermott, J., Menachery, V., Metz, T. O., Mitchell, H., Monroe, M. E., Navarro, G., Neumann, G., Podyminogin, R. L., Purvine, S. O., Rosenberger, C. M., Sanders, C. J., Schepmoes, A. A., Shukla, A. K., Sims, A., Sova, P., Tam, V. C., Tchitchek, N., Thomas, P. G., Tilton, S. C., Totura, A., Wang, J., Webb-Robertson, B. - J., Wen, J., Weiss, J. M., Yang, F., Yount, B., Zhang, Q., McWeeney, S., Smith, R. D., Waters, K. M., Kawaoka, Y., Baric, R., Aderem, A., Katze, M. G., and Scheuermann, R. H., A comprehensive collection of systems biology data characterizing the host response to viral infection, Scientific Data, vol. 1, p. 140033, 2014.
L. K. Siddens, Bunde, K. L., Harper, T. A., McQuistan, T. J., öhr, C. V., Bramer, L. M., Waters, K. M., Tilton, S. C., Krueger, S. K., Williams, D. E., and Baird, W. M., Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse, Toxicology and Applied Pharmacology, vol. 287, no. 2, pp. 149 - 160, 2015.
S. C. Tilton, Matzke, M. M., Sowa, M. B., Stenoien, D. L., Weber, T. J., Morgan, W. F., and Waters, K. M., Data integration reveals key homeostatic mechanisms following low dose radiation exposure, Toxicology and Applied Pharmacology, vol. 285, no. 1, pp. 1 - 11, 2015.
S. C. Tilton, Waters, K. M., Karin, N. J., Webb-Robertson, B. - J. M., Zangar, R. C., K. Lee, M., Bigelow, D. J., Pounds, J. G., and Corley, R. A., Diet-induced obesity reprograms the inflammatory response of the murine lung to inhaled endotoxin, Toxicology and Applied Pharmacology, vol. 267, no. 2, pp. 137 - 148, 2013.
V. Kodali, Littke, M. H., Tilton, S. C., Teeguarden, J. G., Shi, L., Frevert, C. W., Wang, W., Pounds, J. G., and Thrall, B. D., Dysregulation of Macrophage Activation Profiles by Engineered Nanoparticles, ACS Nano, vol. 7, no. 8, pp. 6997 - 7010, 2013.
S. C. Tilton, Karin, N. J., Webb-Robertson, B. - J. M., Waters, K. M., Mikheev, V., K. Lee, M., Corley, R. A., Pounds, J. G., and Bigelow, D. J., Impaired Transcriptional Response of the Murine Heart to Cigarette Smoke in the Setting of High Fat Diet and Obesity, Chemical Research in Toxicology, vol. 26, no. 7, pp. 1034 - 1042, 2013.
J. Tisoncik-Go, Gasper, J., Kyle, E., Eisfeld, J., Selinger, C., Hatta, M., Morrison, J., Korth, J., Zink, M., Kim, Y. - M., Schepmoes, A., Nicora, D., Purvine, O., Weitz, K., Peng, X., Green, R., Tilton, S. C., Webb-Robertson, B. - J., Waters, M., Metz, O., Smith, D., Kawaoka, Y., Suresh, M., Josset, L., and Katze, G., Integrated Omics Analysis of Pathogenic Host Responses during Pandemic H1N1 Influenza Virus Infection: The Crucial Role of Lipid Metabolism, Cell Host & Microbe, vol. 19, no. 2, pp. 254 - 266, 2016.
B. C. Goodale, La Du, J. K., Tilton, S. C., Sullivan, C. M., Bisson, W. H., Waters, K. M., and Tanguay, R., Ligand-specific transcriptional mechanisms underlie aryl hydrocarbon receptor-mediated developmental toxicity of oxygenated PAHs, Toxicological Sciences, p. kfv139, 2015.
S. C. Tilton, Siddens, L. K., Krueger, S. K., Larkin, A. J., Lohr, C. V., Williams, D. E., Baird, W. M., and Waters, K. M., Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential, Toxicological Sciences, vol. 146, no. 1, pp. 135 - 145, 2015.
H. J. Z. Wang X and Tilton, S. C., Metabolite Signatures in Hydrophilic Extracts of Mouse Lungs Exposed to Cigarette Smoke Revealed by 1H NMR Metabolomics Investigation, Journal of Postgenomics Drug & Biomarker Development, vol. 05, no. 02, 2015.
T. L. Tal, Franzosa, J. A., Tilton, S. C., Philbrick, K. A., Iwaniec, U. T., Turner, R. T., Waters, K. M., and Tanguay, R. L., MicroRNAs control neurobehavioral development and function in zebrafish, The FASEB Journal, vol. 26, no. 4, pp. 1452 - 1461, 2012.
J. Cha, Burnum-Johnson, K. E., Bartos, A., Li, Y., Baker, E. S., Tilton, S. C., Webb-Robertson, B. - J. M., Piehowski, P. D., Monroe, M. E., Jegga, A. G., Murata, S., Hirota, Y., and Dey, S. K., Muscle Segment Homeobox Genes Direct Embryonic Diapause by Limiting Inflammation in the Uterus, Journal of Biological Chemistry, vol. 290, no. 24, pp. 15337 - 15349, 2015.
H. D. Mitchell, Eisfeld, A. J., Sims, A. C., McDermott, J. E., Matzke, M. M., Webb-Robertson, B. - J. M., Tilton, S. C., Tchitchek, N., Josset, L., Li, C., Ellis, A. L., Chang, J. H., Heegel, R. A., Luna, M. L., Schepmoes, A. A., Shukla, A. K., Metz, T. O., Neumann, G., Benecke, A. G., Smith, R. D., Baric, R. S., Kawaoka, Y., Katze, M. G., and Waters, K. M., A Network Integration Approach to Predict Conserved Regulators Related to Pathogenicity of Influenza and SARS-CoV Respiratory Viruses, PLoS ONE, vol. 8, no. 7, p. e69374, 2013.
L. K. Siddens, Larkin, A., Krueger, S. K., Bradfield, C. A., Waters, K. M., Tilton, S. C., Pereira, C. B., öhr, C. V., Arlt, V. M., Phillips, D. H., Williams, D. E., and Baird, W. M., Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse, Toxicology and Applied Pharmacology, vol. 264, no. 3, pp. 377 - 386, 2012.
A. C. Sims, Tilton, S. C., Menachery, V. D., Gralinski, L. E., Schafer, A., Matzke, M. M., Webb-Robertson, B. - J. M., Chang, J. H., Luna, M. L., Long, C. E., Shukla, A. K., Bankhead, A. R., Burkett, S. E., Zornetzer, G., Tseng, C. - T. K., Metz, T. O., Pickles, R., McWeeney, S., Smith, R. D., Katze, M. G., Waters, K. M., and Baric, R. S., Release of Severe Acute Respiratory Syndrome Coronavirus Nuclear Import Block Enhances Host Transcription in Human Lung Cells, Journal of Virology, vol. 87, no. 7, pp. 3885 - 3902, 2013.
J. A. Franzosa, Bugel, S. M., Tal, T. L., La Du, J. K., Tilton, S. C., Waters, K. M., and Tanguay, R. L., Retinoic acid-dependent regulation of miR-19 expression elicits vertebrate axis defects, The FASEB Journal, vol. 27, no. 12, pp. 4866 - 4876, 2013.
J. E. McDermott, Costa, M., Janszen, D., Singhal, M., and Tilton, S. C., Separating the drivers from the driven: Integrative network and pathway approaches aid identification of disease biomarkers from high-throughput data., Dis Markers, vol. 28, no. 4, pp. 253-66, 2010.
B. C. Goodale, Tilton, S. C., Corvi, M. M., Wilson, G. R., Janszen, D. B., Anderson, K. A., Waters, K. M., and Tanguay, R. L., Structurally distinct polycyclic aromatic hydrocarbons induce differential transcriptional responses in developing zebrafish, Toxicology and Applied Pharmacology, vol. 272, no. 3, pp. 656 - 670, 2013.
S. C. Tilton, Karin, N. J., Tolic, A., Xie, Y., Lai, X., Hamilton, R. F., Waters, K. M., Holian, A., Witzmann, F. A., and Orr, G., Three human cell types respond to multi-walled carbon nanotubes and titanium dioxide nanobelts with cell-specific transcriptomic and proteomic expression patterns, Nanotoxicology, vol. 8, no. 5, pp. 533 - 548, 2014.